This investigation was made to find the differences in histopathological changes of chronically infected maxillary sinus membrane according to the age.
Fifty-two specimens of maxillary- sinus membrane were taken from the patients who were operated of their diseased sinuses in this college hospital. These were stained by H & E for general inspection, and Ly jYeigert van Gieson for fibrosis of connective tissues,. PAS and Alcian Blue-PAS fer sccreticn cf glands in all cases, after making appropriate-fixation and cuttings.
The histopathological observaticns in each case were made in special points as follows.
1) Edema of mucous membrane
2) Cellular infiltration
3) Changes of epithelium
4) Glands
5) Blood vessels
6) Fibrosis of connective tissue.
All the cases were divided into 4 groups according to the age of patients with 13 cases each, that is, the first group between 14 and 16 years of age, the second group between 17 and 25 years of age, the third group from 26 to 40 years of age and the fourth group above 41 years of age.
The results obtained are as follows:
1. The edema of mucous membrane were more frequently- seen in the second and the third age groups than in the first and the fourth group.
2. In the cellular infiltration, the neutrophils were most rarely seen in the fourth group although the lymphocytes were the most frequently seen in this group and the third group, but the infiltration of ecsirophils and plasma cells were nearly no differences
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